Answer:
Yes. Dr. Jimmy Gutman explains in his latest bestseller "Glutathione (GSH) - Your Key To Health" in Chapter 20- "Psychoneurobiology:" on page 182 about Huntington's Disease:
"Huntington's disease, also known as Huntington's chorea, hereditary chorea, or chronic progressive chorea, is an inherited neurodegenerative movement disorder with progressive intellectual deterioration.
It strikes people between the ages of 35 and 50 and advances relentlessly, leading eventually to a physical and mental inability to look after oneself. The term "chorea" refers to the rapid, complex, jerky motions of the face, trunk, and limbs. The associated dementia is accompanied by psychiatric disturbances as well. Traditional treatments are symptomatic and only minimally effective.
These patients seem to be less able than others to deal with oxidative stress. They suffer from increased free radical generation and decreased GSH defenses.
Studies depleting glutathione from affected tissue show increased damage to and death of these cells. In the laboratory, antioxidants help cells survive. The neurochemical 3-hydroxykynurenine (3-HK) is found in excessive levels in the brains of Huntington's patients and strongly promotes oxidation. Lab experiments using the GSH-enhancing drug NAC seem to reduce the damage done by 3-HK.
O.Bandmann and a team of neurobiologists at the Institute of Neurology in London, think that an inherent defect in the brain's ability to detoxify neurotoxins may be at the root of Huntington's and Parkinson's diseases. Given the importance of glutathione as an antioxidant, its deficiency in these patients will stimulate many more studies."
NAC or N-acetylcysteine is a clinically studied way to raise glutathione. This and all known ways to boost glutathione levels are discussed here.
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